Vitiligo or Vitiligo-like Hypopigmentation Associated with Imiquimod Treatment of Condyloma Acuminatum

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Vitiligo or Vitiligo-like Hypopigmentation Associated with Imiquimod Treatment of Condyloma Acuminatum: Not a Casual Event

During the past 2 years, from January 2014 to December 2015, 6 male patients aged from 27 to 59 years were given imiquimod 5% cream for the treatment of condyloma acuminatum in STD Institute, Shanghai Dermatology Hospital. All patients followed the medicine instructions very carefully when applying the cream. After applying the cream for 1–2 weeks, all of them experienced local skin reactions r...

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Induction of Vitiligo-Like Hypopigmentation after Imiquimod Treatment of Extramammary Paget's Disease

Received November 16, 2011, Revised January 10, 2012, Accepted for publication January 25, 2012 Corresponding author: Kwang Hyun Cho, M.D., Ph.D., Department of Dermatology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 110-744, Korea. Tel: 82-2-2072-2412, Fax: 82-2-742-7344, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative...

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Possible mechanisms in the induction of vitiligo-like hypopigmentation by topical imiquimod.

The pathogenesis of vitiligo was examined for clues to the pigmentary changes that may occur after treatment with topical imiquimod. The literature varies on the pigmentary changes induced by topical use of imiquimod. The US Food and Drugs Administration lists 68 reports of pigmentary changes out of a total of 1257 reports related to imiquimod lodged from 1997 to 2003. Some studies describe vit...

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ژورنال

عنوان ژورنال: Chinese Medical Journal

سال: 2017

ISSN: 0366-6999

DOI: 10.4103/0366-6999.199846